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Of the medicines associated with BIH, minocycline is most frequently reported in the literature! Entretanto, certos testes podem ser solicitados para confirmar o diagnóstico? The binding of tetracycline results in an allosteric conformational change that greatly reduces the affinity of TetR for DNA thereby leaving the divergent promoters available for access by RNA polymerase, whereupon transcription of tetA and tetR is induced?

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